Effect Of Secondary Metabolites Products from Marine Streptomyces Against Bacteria Causing Otitis Media
Sabah A. Abo El-Maaty Mervat G. Hassan, Mohamed E. Elawady, Ahmed A. Hamed, Khaled H. El-harony
The most prevalent and serious illness in the world, otitis media, is typified by fluid accumulation in the middle ear along with acute infection signs and symptoms, which are brought on by bacterial infections. Due to increasing of multi drug resistance bacteria we are in this study use marine Streptomyces specially its secondary metabolites against these multi drug resistance bacteria after isolation and prove that they affected these bacteria. Forty-four are actinomycetes isolates were taken from marine habitats including Hurgada marine sea, Ras Sedr sediment, Ain Sokhna sediment marine sea water, while thirty-six bacterial isolates were obtained from Kafr El-Sheikh General Hospital, Benha University Hospital and Mabaret El-Asafra hospital. The antimicrobial activities of ethyl acetate extracts for isolated Streptomyces spp. Tested using the agar disc diffusion method. 50 µl of each extract culture were soaked on filter paper discs and placed on neutral agar media seeded with isolated bacteria. Antimicrobial activity for Streptomyces extracts isolated from three regions is observed against isolated bacteria.